The simple and naive just-graduated in journalism Andrea Sachs is hired to work as second assistant of the powerful and sophisticated Miranda Priestly, the ruthless and merciless executive of Runway fashion magazine. Andrea dreams of becoming a journalist and faces the opportunity as a temporary professional challenge. First assistant Emily advises Andrea about the behavior and preferences of their cruel boss, and stylist Nigel helps Andrea to dress more adequately for the working environment. Andrea changes her attitude and behavior, which is affecting her private life and the relationship with her boyfriend, her family and friends. In the end, Andrea learns that life is made of choices.